Vitamin B12

Vitamin B12 (cyanocobalamin) is a cobalt-corrinoid coenzyme with a central cobalt(III) ion coordinated by a corrin ring, an axial dimethylbenzimidazole, and an axial cyano ligand. Empirical formula C₆₃H₈₈CoN₁₄O₁₄P; MW 1355.37 Da (PubChem CID 5479262).

Reconstitution. For in-vitro laboratory handling, dissolve with sterile water. Compound is hygroscopic — handle in low-humidity conditions and re-cap immediately.

Stability profile. Lyophilized: stable at room temperature for up to 30 days sealed; long-term storage at -20 °C recommended. Reconstituted material: stable at 2–8 °C for up to 14 days.

Selected primary literature.
- Hodgkin DC et al., 1956, Nature 178(4524):64 — original X-ray crystallographic structural determination of cyanocobalamin.

What remains uncharacterized: cyanocobalamin is a coenzyme, not a peptide. The cited literature describes structural and crystallographic observations; downstream biological outcomes in any specific model system are not implied here.

For research use only. Not for human or animal consumption.

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