Glutathione

Glutathione is a linear tripeptide with a non-canonical γ-peptide bond between the glutamate γ-carboxylate and the cysteine α-amine. Empirical formula C₁₀H₁₇N₃O₆S; MW 307.32 Da (PubChem CID 124886). The free thiol on the cysteine residue is the chemically reactive group.

Reconstitution. For in-vitro laboratory handling, dissolve with sterile water. Compound is hygroscopic — handle in low-humidity conditions and re-cap immediately.

Stability profile. Lyophilized: stable at room temperature for up to 30 days sealed; long-term storage at -20 °C recommended. Reconstituted material: stable at 2–8 °C for up to 14 days.

Selected primary literature.
- Meister A & Anderson ME, 1983, Annu Rev Biochem 52:711 — review of the structural biochemistry of glutathione metabolism.

What remains uncharacterized: glutathione is a small-molecule cofactor; downstream biological outcomes in any specific model system are not implied here.

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