MOTS-c

MOTS-c is a 16-residue peptide encoded within an alternative open reading frame of the mitochondrial 12S rRNA (MT-RNR1) locus. Sequence: MRWQEMGYIFYPRKLR. Empirical formula C₁₀₀H₁₅₇N₃₁O₂₅S₂; MW 2174.59 Da.

Reconstitution. For in-vitro laboratory handling, dissolve with bacteriostatic water (0.9% benzyl alcohol). Compound is hygroscopic — handle in low-humidity conditions and re-cap immediately.

Stability profile. Lyophilized: stable at room temperature for up to 30 days sealed; long-term storage at -20 °C recommended. Reconstituted material: stable at 2–8 °C for up to 14 days.

Selected primary literature.
- Lee C et al., 2015, Cell Metab 21(3):443 — identification and structural characterization of the MOTS-c mitochondrial-derived peptide (preclinical in-vitro and primary-cell-culture study).

What remains uncharacterized: concentration-response relationships in any specific in-vitro model system are not implied here. The literature cited above describes molecular-level observations only.

For research use only. Not for human or animal consumption.

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