About the compound
Heterodimeric placental glycoprotein hormone (α + β-hCG subunits) — ~36.7 kDa, approximately 30% carbohydrate by mass.
Human chorionic gonadotropin is a non-covalent heterodimer of a 92-residue α-subunit (UniProt P01215) and a 145-residue β-hCG subunit (UniProt P01233). Eight N- and O-linked glycans contribute approximately 30% of the molecular mass; the precise MW depends on glycoform, with the most common preparation centering near 36 700 Da.
Reconstitution. For in-vitro laboratory handling, dissolve with bacteriostatic water (0.9% benzyl alcohol). Compound is hygroscopic — handle in low-humidity conditions and re-cap immediately.
Stability profile. Lyophilized: stable at room temperature for up to 30 days sealed; long-term storage at -20 °C recommended. Reconstituted material: stable at 2–8 °C for up to 14 days.
Selected primary literature.
- Lapthorn AJ et al., 1994, Nature 369(6480):455 — crystal structure of the αβ heterodimer at 2.6 Å (preclinical structural study).
- Cole LA, 2010, Reprod Biol Endocrinol 8:102 — review of the hCG isoform family and their differential carbohydrate composition.
What remains uncharacterized: concentration-response relationships in any specific in-vitro model system are not implied here. The literature cited above describes molecular-level observations only.
For research use only. Not for human or animal consumption.
