CJC-1295 DAC

CJC-1295 with the drug-affinity-complex (DAC) handle is a 30-residue analog of GHRH(1-29). The modified residues D-Ala2, Gln8, Ala15, and Leu27 confer resistance to DPP-4 cleavage. A C-terminal Lys30 bears a maleimidopropionic acid (MPA) handle that forms an in-situ thioether bond with the free thiol of Cys34 on serum albumin.

Reconstitution. For in-vitro laboratory handling, dissolve with bacteriostatic water (0.9% benzyl alcohol). Compound is hygroscopic — handle in low-humidity conditions and re-cap immediately.

Stability profile. Lyophilized: stable at room temperature for up to 30 days sealed; long-term storage at -20 °C recommended. Reconstituted material: stable at 2–8 °C for up to 14 days.

Selected primary literature.
- Jetté L et al., 2005, Endocrinology 146(7):3052 — discovery and structural characterization of the GHRH(1-29) DAC analog (preclinical in-vitro albumin-binding study).

What remains uncharacterized: concentration-response relationships in any specific in-vitro model system are not implied here. The literature cited above describes molecular-level observations only.

For research use only. Not for human or animal consumption.

By placing an order with Verified Compounds, you acknowledge and confirm that:
- All products are intended exclusively for in-vitro research and laboratory use only.
- Products are not intended for human or animal consumption, nor for diagnostic, therapeutic, or clinical applications.
- You are familiar with your jurisdiction's regulations regarding research chemicals and their proper handling.
- You understand the safety protocols required for handling research peptides and will ensure proper storage.
- You are at least 21 years of age and represent a qualified research institution or are a licensed researcher.
- Verified Compounds, this website, and our affiliates are not responsible for how you use or store these items once delivered, to the fullest extent allowed by law.