LL-37

LL-37 is the sole human cathelicidin antimicrobial peptide, processed from the C-terminus of the hCAP18 precursor (UniProt P49913). Sequence: LLGDFFRKSKEKIGKEFKRIVQRIKDFLRNLVPRTES. Empirical formula C₂₀₅H₃₄₀N₆₀O₅₃; MW 4493.27 Da.

Reconstitution. For in-vitro laboratory handling, dissolve with bacteriostatic water (0.9% benzyl alcohol). Compound is hygroscopic — handle in low-humidity conditions and re-cap immediately.

Stability profile. Lyophilized: stable at room temperature for up to 30 days sealed; long-term storage at -20 °C recommended. Reconstituted material: stable at 2–8 °C for up to 14 days.

Selected primary literature.
- Gudmundsson GH et al., 1996, Eur J Biochem 238(2):325 — original isolation and structural characterization of LL-37 (preclinical).

What remains uncharacterized: concentration-response relationships in any specific in-vitro model system are not implied here. The literature cited above describes molecular-level observations only.

For research use only. Not for human or animal consumption.

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