About the compound
Alanyl-histidyl-lysine tripeptide complexed with Cu(II). Reported MW ~415.94 Da (chloride salt).
AHK-Cu is a 1:1 complex of the tripeptide Ala-His-Lys with Cu(II). Cu(II) coordinates via the histidine imidazole, the N-terminal amine, and a deprotonated amide nitrogen. Empirical formula C₁₅H₂₆N₆O₄·Cu; reported MW ~415.94 Da for the AHK·Cu·Cl salt.
Reconstitution. For in-vitro laboratory handling, dissolve with sterile water. Compound is hygroscopic — handle in low-humidity conditions and re-cap immediately.
Stability profile. Lyophilized: stable at room temperature for up to 30 days sealed; long-term storage at -20 °C recommended. Reconstituted material: stable at 2–8 °C for up to 14 days.
Selected primary literature.
- Pickart L & Margolina A, 2018, Int J Mol Sci 19(7):1987 — structural review of the GHK / AHK-Cu(II) coordination chemistry (preclinical).
What remains uncharacterized: concentration-response relationships in any specific in-vitro model system are not implied here. The literature cited above describes molecular-level observations only.
For research use only. Not for human or animal consumption.




