FST 344 (Follistatin 344)

Follistatin-344 is the long isoform of human follistatin (UniProt P19883, residues 30–373), comprising an N-terminal domain followed by three follistatin domains (FSD1–FSD3) and a heparin-binding C-terminus. The unglycosylated mature chain has an MW of approximately 38 kDa; glycoforms run between 30 and 35 kDa on SDS-PAGE.

Reconstitution. Solubility is highest in 0.1% acetic acid or in DMSO; bacteriostatic water suffices for most applications. Avoid alkaline buffers (pH > 8) for prolonged exposure.

Stability profile. Lyophilized: stable at room temperature for up to 30 days sealed; long-term storage at -20 °C recommended. Reconstituted material: stable at 2–8 °C for up to 14 days.

Selected primary literature.
- Innis CA & Hyvönen M, 2003, J Biol Chem 278(40):39969 — structural characterization of the follistatin / activin complex (preclinical in-vitro binding study).

What remains uncharacterized: concentration-response relationships in any specific in-vitro model system are not implied here. The literature cited above describes molecular-level observations only.

For research use only. Not for human or animal consumption.

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