TB-500 (Frag 17-23 of Thymosin Beta-4)

TB-500 is the acetylated free-acid heptapeptide Ac-Leu-Lys-Lys-Thr-Glu-Thr-Gln, corresponding to residues 17–23 of thymosin β-4. Empirical formula C₃₉H₆₈N₁₀O₁₄; MW 889.0 Da. Distinct from full-length Tβ4 (a 43-residue peptide).

Reconstitution. For in-vitro laboratory handling, dissolve with bacteriostatic water (0.9% benzyl alcohol). Compound is hygroscopic — handle in low-humidity conditions and re-cap immediately.

Stability profile. Lyophilized: stable at room temperature for up to 30 days sealed; long-term storage at -20 °C recommended. Reconstituted material: stable at 2–8 °C for up to 14 days.

Selected primary literature.
- Sosne G et al., 2010, Expert Opin Biol Ther 10(7):1093 — structural review of the actin-binding LKKTET motif of Tβ4 (preclinical).

What remains uncharacterized: concentration-response relationships in any specific in-vitro model system are not implied here. The literature cited above describes molecular-level observations only.

For research use only. Not for human or animal consumption.

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