PEG-MGF

PEG-MGF is the MGF peptide arm (24 residues: YQPPSTNKNTKSQRRKGSTFEERK) conjugated to a poly(ethylene glycol) chain at the N-terminus. PEG arm length is vendor-specific (1, 2, or 5 kDa is typical); the total MW therefore varies by lot. The peptide moiety is identical to unmodified MGF.

Reconstitution. For in-vitro laboratory handling, dissolve with bacteriostatic water (0.9% benzyl alcohol). Compound is hygroscopic — handle in low-humidity conditions and re-cap immediately.

Stability profile. Lyophilized: stable at room temperature for up to 30 days sealed; long-term storage at -20 °C recommended. Reconstituted material: stable at 2–8 °C for up to 14 days.

Selected primary literature.
- Goldspink G, 2005, J Anat 206(5):437 — structural review of the IGF-1Ec splice variant and the rationale for PEGylated E-domain conjugates (preclinical).

What remains uncharacterized: concentration-response relationships in any specific in-vitro model system are not implied here. The literature cited above describes molecular-level observations only.

For research use only. Not for human or animal consumption.

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