Gonadorelin (GnRH)

Gonadorelin is the native human gonadotropin-releasing hormone decapeptide with a pyroglutamate-blocked N-terminus and a C-terminal amide. Empirical formula C₅₅H₇₅N₁₇O₁₃; MW 1182.31 Da (PubChem CID 638793).

Reconstitution. For in-vitro laboratory handling, dissolve with bacteriostatic water (0.9% benzyl alcohol). Compound is hygroscopic — handle in low-humidity conditions and re-cap immediately.

Stability profile. Lyophilized: stable at room temperature for up to 30 days sealed; long-term storage at -20 °C recommended. Reconstituted material: stable at 2–8 °C for up to 14 days.

Selected primary literature.
- Schally AV et al., 1971, Science 173(3997):1036 — original isolation, sequencing, and structural characterization of GnRH (preclinical).

What remains uncharacterized: concentration-response relationships in any specific in-vitro model system are not implied here. The literature cited above describes molecular-level observations only.

For research use only. Not for human or animal consumption.

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