B7-33

B7-33 is a single-chain analog of human relaxin-2 designed without the A-chain or its disulfides. Sequence: YDLWKEAAVEEDQSAILEEDDSGRSAS. Empirical formula C₁₂₉H₁₉₂N₃₂O₅₀; MW 2961.13 Da.

Reconstitution. For in-vitro laboratory handling, dissolve with bacteriostatic water (0.9% benzyl alcohol). Compound is hygroscopic — handle in low-humidity conditions and re-cap immediately.

Stability profile. Lyophilized: stable at room temperature for up to 30 days sealed; long-term storage at -20 °C recommended. Reconstituted material: stable at 2–8 °C for up to 14 days.

Selected primary literature.
- Hossain MA et al., 2016, Chem Sci 7(6):3805 — structural design and in-vitro RXFP1-receptor characterization of the single-B-chain relaxin-2 analog (preclinical).

What remains uncharacterized: concentration-response relationships in any specific in-vitro model system are not implied here. The literature cited above describes molecular-level observations only.

For research use only. Not for human or animal consumption.

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